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Frequency of CHEK2 mutations in a population based, case–control study of breast cancer in young women

INTRODUCTION: The cell-cycle checkpoint kinase (CHEK)2 protein truncating mutation 1100delC has been associated with increased risk for breast or prostate cancer. Multiple studies have found an elevated frequency of the 1100delC variant in specific stratifications of breast cancer patients with a fa...

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Detalles Bibliográficos
Autores principales: Friedrichsen, Danielle M, Malone, Kathleen E, Doody, David R, Daling, Janet R, Ostrander, Elaine A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064080/
https://www.ncbi.nlm.nih.gov/pubmed/15535844
http://dx.doi.org/10.1186/bcr933