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Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview

The breast tissue is the site of major metabolic conversions of estradiol (E(2)) mediated by specific cytochromes P450 hydroxylations and methylation by catechol-O-methytransferase. In addition to E(2 )itself, recent findings highlight the significance of 4-hydroxylated estrogen metabolites as chemi...

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Detalles Bibliográficos
Autores principales: Guillemette, Chantal, Bélanger, Alain, Lépine, Johanie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064083/
https://www.ncbi.nlm.nih.gov/pubmed/15535854
http://dx.doi.org/10.1186/bcr936