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Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview
The breast tissue is the site of major metabolic conversions of estradiol (E(2)) mediated by specific cytochromes P450 hydroxylations and methylation by catechol-O-methytransferase. In addition to E(2 )itself, recent findings highlight the significance of 4-hydroxylated estrogen metabolites as chemi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064083/ https://www.ncbi.nlm.nih.gov/pubmed/15535854 http://dx.doi.org/10.1186/bcr936 |