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Dual Delivery of Tetramethylpyrazine and miR-194-5p Using Soft Mesoporous Organosilica Nanoparticles for Acute Lung Injury Therapy

BACKGROUND: The respiratory system is intensely damaged by acute lung injury (ALI). The anti-inflammatory effects of tetramethylpyrazine (TMP) against ALI have been confirmed, but it exhibits a short half-life. miR-194-5p could directly target Rac1, but the internalization rate of miRNA cells was lo...

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Detalles Bibliográficos
Autores principales: Min, Simin, Tao, Weiting, Miao, Yuchen, Li, Yan, Wu, Tianyu, He, Xiaoyu, Zhang, Yijing, Liu, Bangye, Meng, Zixin, Han, Ke, Liu, Saisai, Li, Li, Chen, Jie, Zhao, Shidi, Zhang, Junjie, Zhang, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640848/
https://www.ncbi.nlm.nih.gov/pubmed/38026537
http://dx.doi.org/10.2147/IJN.S420802