The p53-dependent apoptotic pathway of breast cancer cells (BC-M1) induced by the bis-type bioreductive compound aziridinylnaphthoquinone

INTRODUCTION: Several aziridinylbenzoquinone drugs have undergone clinical trials as potential antitumor drugs. These bioreductive compounds are designed to kill cells preferentially within the hypoxia tumor microenvironment. The bioreductive compound of bis-type naphthoquinone synthesized in our la...

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Detalles Bibliográficos
Autores principales: Yang, Yu-Ping, Kuo, Hsien-Shou, Tsai, Hsin-Da, Peng, Yi-Chen, Lin, Yuh-Ling
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064093/
https://www.ncbi.nlm.nih.gov/pubmed/15642166
http://dx.doi.org/10.1186/bcr939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064093/
https://www.ncbi.nlm.nih.gov/pubmed/15642166
http://dx.doi.org/10.1186/bcr939

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