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The p53-dependent apoptotic pathway of breast cancer cells (BC-M1) induced by the bis-type bioreductive compound aziridinylnaphthoquinone

INTRODUCTION: Several aziridinylbenzoquinone drugs have undergone clinical trials as potential antitumor drugs. These bioreductive compounds are designed to kill cells preferentially within the hypoxia tumor microenvironment. The bioreductive compound of bis-type naphthoquinone synthesized in our la...

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Detalles Bibliográficos
Autores principales:	Yang, Yu-Ping, Kuo, Hsien-Shou, Tsai, Hsin-Da, Peng, Yi-Chen, Lin, Yuh-Ling
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064093/ https://www.ncbi.nlm.nih.gov/pubmed/15642166 http://dx.doi.org/10.1186/bcr939

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