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Clonal redemption of B cells in cancer

Potentially self-reactive B cells constitute a large portion of the peripheral B cell repertoire in both mice and humans. Maintenance of autoreactive B cell populations could conceivably be detrimental to the host but their conservation throughout evolution suggests performance of a critical and ben...

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Detalles Bibliográficos
Autores principales: McCaw, Tyler R., Lofftus, Serena Y., Crompton, Joseph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640973/
https://www.ncbi.nlm.nih.gov/pubmed/37965337
http://dx.doi.org/10.3389/fimmu.2023.1277597