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Intra- and inter-molecular regulation by intrinsically-disordered regions governs PUF protein RNA binding

PUF proteins are characterized by globular RNA-binding domains. They also interact with partner proteins that modulate their RNA-binding activities. Caenorhabditis elegans PUF protein fem-3 binding factor-2 (FBF-2) partners with intrinsically disordered Lateral Signaling Target-1 (LST-1) to regulate...

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Detalles Bibliográficos
Autores principales: Qiu, Chen, Zhang, Zihan, Wine, Robert N., Campbell, Zachary T., Zhang, Jun, Hall, Traci M. Tanaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641069/
https://www.ncbi.nlm.nih.gov/pubmed/37953271
http://dx.doi.org/10.1038/s41467-023-43098-1