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Atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout mice

INTRODUCTION: Ataxia-telangiectasia is an autosomal-recessive disease that affects neuro-immunological functions, associated with increased susceptibility to malignancy, chromosomal instability and hypersensitivity to ionizing radiation. Although ataxia-telangiectasia mutated (ATM) heterozygous defi...

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Detalles Bibliográficos
Autores principales: Umesako, Seiichi, Fujisawa, Kae, Iiga, Sayoko, Mori, Nobuko, Takahashi, Masahiro, Hong, Doo-Pyo, Song, Chang-Woo, Haga, Satomi, Imai, Syunsuke, Niwa, Otsura, Okumoto, Masaaki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064114/
https://www.ncbi.nlm.nih.gov/pubmed/15642165
http://dx.doi.org/10.1186/bcr968