Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis

Osteoarthritis (OA) is a prevalent chronic degenerative joint disease worldwide. Obesity has been linked to OA, and increased free fatty acid levels (e.g., palmitate) contribute to inflammatory responses and cartilage degradation. Xanthohumol (Xn), a bioactive prenylated chalcone, was shown to exhib...

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Detalles Bibliográficos
Autores principales: Sun, Weichao, Yue, Jiaji, Xu, Tianhao, Cui, Yinxing, Huang, Dixi, Shi, Houyin, Xiong, Jianyi, Sun, Wei, Yi, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641167/
https://www.ncbi.nlm.nih.gov/pubmed/37964828
http://dx.doi.org/10.1016/j.heliyon.2023.e21282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641167/
https://www.ncbi.nlm.nih.gov/pubmed/37964828
http://dx.doi.org/10.1016/j.heliyon.2023.e21282

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