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A multiple-oscillator mechanism underlies antigen-induced Ca(2+) oscillations in Jurkat T-cells

T-cell receptor stimulation triggers cytosolic Ca(2+) signaling by inositol-1,4,5-trisphosphate (IP(3))-mediated Ca(2+) release from the endoplasmic reticulum (ER) and Ca(2+) entry through Ca(2+) release-activated Ca(2+) (CRAC) channels gated by ER-located stromal-interacting molecules (STIM1/2). Ph...

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Detalles Bibliográficos
Autores principales: Benson, J. Cory, Romito, Olivier, Abdelnaby, Ahmed Emam, Xin, Ping, Pathak, Trayambak, Weir, Sierra E., Kirk, Vivien, Castaneda, Francisco, Yoast, Ryan E., Emrich, Scott M., Tang, Priscilla W., Yule, David I., Hempel, Nadine, Potier-Cartereau, Marie, Sneyd, James, Trebak, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641176/
https://www.ncbi.nlm.nih.gov/pubmed/37778728
http://dx.doi.org/10.1016/j.jbc.2023.105310