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B4GALNT1 promotes hepatocellular carcinoma stemness and progression via integrin α2β1-mediated FAK and AKT activation

BACKGROUND & AIMS: β-1,4-N-Acetyl-galactosaminyltransferase 1 (B4GALNT1) has been reported to contribute to the development of human malignancies. However, its role in hepatocellular carcinoma (HCC) remains uncharacterised. In this study, we aimed to elucidate the role of B4GALNT1 in HCC stemnes...

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Detalles Bibliográficos
Autores principales: Tang, Yao, Xu, Zhijie, Xu, Fuyuan, Ye, Juan, Chen, Jianxu, He, Jianzhong, Chen, Yingchun, Qi, Chunhui, Huang, Hongbin, Liu, Ruiyang, Shan, Hong, Xiao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641234/
https://www.ncbi.nlm.nih.gov/pubmed/37965158
http://dx.doi.org/10.1016/j.jhepr.2023.100903