Cargando…
B4GALNT1 promotes hepatocellular carcinoma stemness and progression via integrin α2β1-mediated FAK and AKT activation
BACKGROUND & AIMS: β-1,4-N-Acetyl-galactosaminyltransferase 1 (B4GALNT1) has been reported to contribute to the development of human malignancies. However, its role in hepatocellular carcinoma (HCC) remains uncharacterised. In this study, we aimed to elucidate the role of B4GALNT1 in HCC stemnes...
Autores principales: | Tang, Yao, Xu, Zhijie, Xu, Fuyuan, Ye, Juan, Chen, Jianxu, He, Jianzhong, Chen, Yingchun, Qi, Chunhui, Huang, Hongbin, Liu, Ruiyang, Shan, Hong, Xiao, Fei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641234/ https://www.ncbi.nlm.nih.gov/pubmed/37965158 http://dx.doi.org/10.1016/j.jhepr.2023.100903 |
Ejemplares similares
-
SETD1A drives stemness by reprogramming the epigenetic landscape in hepatocellular carcinoma stem cells
por: Chen, Jianxu, et al.
Publicado: (2023) -
β1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway
por: Tian, Tao, et al.
Publicado: (2018) -
Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway
por: Huang, Chun-Yung, et al.
Publicado: (2009) -
SPP1 promotes ovarian cancer progression via Integrin β1/FAK/AKT signaling pathway
por: Zeng, Biao, et al.
Publicado: (2018) -
Activation of the integrins α5β1 and αvβ3 and focal adhesion kinase (FAK) during arteriogenesis
por: Cai, Wei-Jun, et al.
Publicado: (2008)