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Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma

Osteosarcoma is a devastating bone cancer that disproportionally afflicts children, adolescents, and young adults. Standard therapy includes surgical tumor resection combined with multiagent chemotherapy, but many patients still suffer from metastatic disease progression. Neoadjuvant systemic oncoly...

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Detalles Bibliográficos
Autores principales: Makielski, Kelly M., Sarver, Aaron L., Henson, Michael S., Stuebner, Kathleen M., Borgatti, Antonella, Suksanpaisan, Lukkana, Preusser, Caitlin, Tabaran, Alexandru-Flaviu, Cornax, Ingrid, O’Sullivan, M. Gerard, Chehadeh, Andrea, Groschen, Donna, Bergsrud, Kelly, Pracht, Sara, Winter, Amber, Mills, Lauren J., Schwabenlander, Marc D., Wolfe, Melissa, Farrar, Michael A., Cutter, Gary R., Koopmeiners, Joseph S., Russell, Stephen J., Modiano, Jaime F., Naik, Shruthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641240/
https://www.ncbi.nlm.nih.gov/pubmed/37965295
http://dx.doi.org/10.1016/j.omto.2023.100736