The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers

INTRODUCTION: The androgen receptor (AR) gene exon 1 CAG repeat polymorphism encodes a string of 9–32 glutamines. Women with germline BRCA1 mutations who carry at least one AR allele with 28 or more repeats have been reported to have an earlier age at onset of breast cancer. METHODS: A total of 604...

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Detalles Bibliográficos
Autores principales: Spurdle, Amanda B, Antoniou, Antonis C, Duffy, David L, Pandeya, Nirmala, Kelemen, Livia, Chen, Xiaoqing, Peock, Susan, Cook, Margaret R, Smith, Paula L, Purdie, David M, Newman, Beth, Dite, Gillian S, Apicella, Carmel, Southey, Melissa C, Giles, Graham G, Hopper, John L, Chenevix-Trench, Georgia, Easton, Douglas F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064126/
https://www.ncbi.nlm.nih.gov/pubmed/15743497
http://dx.doi.org/10.1186/bcr971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064126/
https://www.ncbi.nlm.nih.gov/pubmed/15743497
http://dx.doi.org/10.1186/bcr971

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