Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi

Tick serine protease inhibitors (serpins) play crucial roles in tick feeding and pathogen transmission. We demonstrate that Ixodes scapularis (Ixs) nymph tick saliva serpin (S) 41 (IxsS41), secreted by Borrelia burgdorferi (Bb)-infected ticks at high abundance, is involved in regulating tick evasion...

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Detalles Bibliográficos
Autores principales: Bencosme-Cuevas, Emily, Kim, Tae Kwon, Nguyen, Thu-Thuy, Berry, Jacquie, Li, Jianrong, Adams, Leslie Garry, Smith, Lindsey A., Batool, Syeda Areeha, Swale, Daniel R., Kaufmann, Stefan H. E., Jones-Hall, Yava, Mulenga, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641286/
https://www.ncbi.nlm.nih.gov/pubmed/37965264
http://dx.doi.org/10.3389/fcimb.2023.1253670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641286/
https://www.ncbi.nlm.nih.gov/pubmed/37965264
http://dx.doi.org/10.3389/fcimb.2023.1253670

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