A protocol for simultaneous high-sensitivity genotyping and chromatin accessibility profiling in single cells

Single-cell assay for transposase-accessible chromatin with sequencing (scATAC-seq) resolves the heterogeneity of epigenetic states across cells but does not typically capture exonic mutations, which limits our knowledge of how somatic mutations alter chromatin landscapes. Here, we present a plate-b...

Descripción completa

Detalles Bibliográficos
Autores principales: Turkalj, Sven, Jakobsen, Niels Asger, Groom, Angus, Radtke, Felix A., Vyas, Paresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641301/
https://www.ncbi.nlm.nih.gov/pubmed/37897733
http://dx.doi.org/10.1016/j.xpro.2023.102641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641301/
https://www.ncbi.nlm.nih.gov/pubmed/37897733
http://dx.doi.org/10.1016/j.xpro.2023.102641

Ejemplares similares