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A protocol for simultaneous high-sensitivity genotyping and chromatin accessibility profiling in single cells
Single-cell assay for transposase-accessible chromatin with sequencing (scATAC-seq) resolves the heterogeneity of epigenetic states across cells but does not typically capture exonic mutations, which limits our knowledge of how somatic mutations alter chromatin landscapes. Here, we present a plate-b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641301/ https://www.ncbi.nlm.nih.gov/pubmed/37897733 http://dx.doi.org/10.1016/j.xpro.2023.102641 |