High expression of focal adhesion kinase (p125(FAK)) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome

INTRODUCTION: Focal adhesion kinase (FAK) regulates multiple cellular processes including growth, differentiation, adhesion, motility and apoptosis. In breast carcinoma, FAK overexpression has been linked to cancer progression but the prognostic relevance remains unknown. In particular, with regard...

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Detalles Bibliográficos
Autores principales: Schmitz, Klaus Jürgen, Grabellus, Florian, Callies, Rainer, Otterbach, Friedrich, Wohlschlaeger, Jeremias, Levkau, Bodo, Kimmig, Rainer, Schmid, Kurt Werner, Baba, Hideo Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064131/
https://www.ncbi.nlm.nih.gov/pubmed/15743500
http://dx.doi.org/10.1186/bcr977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064131/
https://www.ncbi.nlm.nih.gov/pubmed/15743500
http://dx.doi.org/10.1186/bcr977

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