DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia

Patients with relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL) have a poor prognosis with few therapeutic options. With the goal of identifying novel therapeutic targets, we used data from the Dependency Map project to identify dihydroorotate dehydrogenase (DHODH) as one of the top...

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Detalles Bibliográficos
Autores principales: Sexauer, Amy N., Alexe, Gabriela, Gustafsson, Karin, Zanetakos, Elizabeth, Milosevic, Jelena, Ayres, Mary, Gandhi, Varsha, Pikman, Yana, Stegmaier, Kimberly, Sykes, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641474/
https://www.ncbi.nlm.nih.gov/pubmed/37648673
http://dx.doi.org/10.1182/bloodadvances.2023010337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641474/
https://www.ncbi.nlm.nih.gov/pubmed/37648673
http://dx.doi.org/10.1182/bloodadvances.2023010337

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