Safety and efficacy of glibenclamide combined with rtPA in acute cerebral ischemia with occlusion/stenosis of anterior circulation (SE-GRACE): a randomized, double-blind, placebo-controlled trial

BACKGROUND: Glibenclamide alleviates brain edema and improves neurological outcomes in experimental models of stroke. We aimed to assess whether glibenclamide improves functional outcomes in patients with acute ischemic stroke treated with recombinant tissue plasminogen activator (rtPA). METHODS: In...

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Detalles Bibliográficos
Autores principales: Huang, Kaibin, Zhao, Xiaolin, Zhao, Yunxiao, Yang, Guoshuai, Zhou, Saijun, Yang, Zhi, Huang, Wenguo, Weng, Guohu, Chen, Pingyan, Duan, Chongyang, Lin, Zhenzhou, Wang, Shengnan, Liu, Xiangmin, Huang, Yunqiang, Zhang, Jiangshan, Zhang, Xu, Li, Hao, Ye, Songsheng, Gu, Yong, Zhu, Minzhen, Chen, Weiying, Quan, Weiwei, Liu, Na, Chen, Quanfeng, Chang, Yuan, He, Jinzhao, Ji, Zhong, Wu, Yongming, Pan, Suyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641480/
https://www.ncbi.nlm.nih.gov/pubmed/37965431
http://dx.doi.org/10.1016/j.eclinm.2023.102305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641480/
https://www.ncbi.nlm.nih.gov/pubmed/37965431
http://dx.doi.org/10.1016/j.eclinm.2023.102305

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