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Multiple instance learning to predict immune checkpoint blockade efficacy using neoantigen candidates

Previous studies showed that the neoantigen candidate load is an imperfect predictor of immune checkpoint blockade (ICB) efficacy. Further studies provided evidence that the response to ICB is also affected by the qualitative properties of a few or even single candidates, limiting the predictive pow...

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Detalles Bibliográficos
Autores principales: Lang, Franziska, Sorn, Patrick, Schrörs, Barbara, Weber, David, Kramer, Stefan, Sahin, Ugur, Löwer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641489/
https://www.ncbi.nlm.nih.gov/pubmed/37965155
http://dx.doi.org/10.1016/j.isci.2023.108014