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Multiple instance learning to predict immune checkpoint blockade efficacy using neoantigen candidates
Previous studies showed that the neoantigen candidate load is an imperfect predictor of immune checkpoint blockade (ICB) efficacy. Further studies provided evidence that the response to ICB is also affected by the qualitative properties of a few or even single candidates, limiting the predictive pow...
Autores principales: | Lang, Franziska, Sorn, Patrick, Schrörs, Barbara, Weber, David, Kramer, Stefan, Sahin, Ugur, Löwer, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641489/ https://www.ncbi.nlm.nih.gov/pubmed/37965155 http://dx.doi.org/10.1016/j.isci.2023.108014 |
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