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Determining the structure of protein-bound ceramides, essential lipids for skin barrier function

Protein-bound ceramides, specialized ceramides covalently bound to corneocyte surface proteins, are essential for skin permeability barrier function. However, their exact structure and target amino acid residues are unknown. Here, we found that epoxy-enone (EE) ceramides, precursors of protein-bound...

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Detalles Bibliográficos
Autores principales: Ohno, Yusuke, Nakamura, Tetsuya, Iwasaki, Takafumi, Katsuyama, Akira, Ichikawa, Satoshi, Kihara, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641502/
https://www.ncbi.nlm.nih.gov/pubmed/37965138
http://dx.doi.org/10.1016/j.isci.2023.108248