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Determining the structure of protein-bound ceramides, essential lipids for skin barrier function
Protein-bound ceramides, specialized ceramides covalently bound to corneocyte surface proteins, are essential for skin permeability barrier function. However, their exact structure and target amino acid residues are unknown. Here, we found that epoxy-enone (EE) ceramides, precursors of protein-bound...
Autores principales: | Ohno, Yusuke, Nakamura, Tetsuya, Iwasaki, Takafumi, Katsuyama, Akira, Ichikawa, Satoshi, Kihara, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641502/ https://www.ncbi.nlm.nih.gov/pubmed/37965138 http://dx.doi.org/10.1016/j.isci.2023.108248 |
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