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Structural insights of the p97/VCP AAA+ ATPase: How adapter interactions coordinate diverse cellular functionality
p97/valosin-containing protein is an essential eukaryotic AAA+ ATPase with diverse functions including protein homeostasis, membrane remodeling, and chromatin regulation. Dysregulation of p97 function causes severe neurodegenerative disease and is associated with cancer, making this protein a signif...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641518/ https://www.ncbi.nlm.nih.gov/pubmed/37611827 http://dx.doi.org/10.1016/j.jbc.2023.105182 |