Single-cell transcriptomics reveals subtype-specific molecular profiles in Nrf2-deficient macrophages from murine atherosclerotic aortas

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcriptional regulator of antioxidant and anti-inflammatory response in all cell types. It also activates the transcription of genes important for macrophage function. Nrf2 activity declines with age and has been closely linked to atheroscle...

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Detalles Bibliográficos
Autores principales: Sarad, Katarzyna, Stefańska, Monika, Kraszewska, Izabela, Szade, Krzysztof, Sluimer, Judith C., Błyszczuk, Przemysław, Dulak, Józef, Jaźwa-Kusior, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641521/
https://www.ncbi.nlm.nih.gov/pubmed/37965327
http://dx.doi.org/10.3389/fimmu.2023.1249379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641521/
https://www.ncbi.nlm.nih.gov/pubmed/37965327
http://dx.doi.org/10.3389/fimmu.2023.1249379

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