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Single-cell transcriptomics reveals subtype-specific molecular profiles in Nrf2-deficient macrophages from murine atherosclerotic aortas
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcriptional regulator of antioxidant and anti-inflammatory response in all cell types. It also activates the transcription of genes important for macrophage function. Nrf2 activity declines with age and has been closely linked to atheroscle...
Autores principales: | Sarad, Katarzyna, Stefańska, Monika, Kraszewska, Izabela, Szade, Krzysztof, Sluimer, Judith C., Błyszczuk, Przemysław, Dulak, Józef, Jaźwa-Kusior, Agnieszka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641521/ https://www.ncbi.nlm.nih.gov/pubmed/37965327 http://dx.doi.org/10.3389/fimmu.2023.1249379 |
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