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Serum opacity factor normalizes erythrocyte morphology in Scarb1(−/−) mice in an HDL-free cholesterol-dependent way

Compared with WT mice, HDL receptor-deficient (Scarb1(−/−)) mice have higher plasma levels of free cholesterol (FC)-rich HDL and exhibit multiple pathologies associated with a high mol% FC in ovaries, platelets, and erythrocytes, which are reversed by lowering HDL. Bacterial serum opacity factor (SO...

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Detalles Bibliográficos
Autores principales: Wang, Ziyi, Yelamanchili, Dedipya, Liu, Jing, Gotto, Antonio M., Rosales, Corina, Gillard, Baiba K., Pownall, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641538/
https://www.ncbi.nlm.nih.gov/pubmed/37821077
http://dx.doi.org/10.1016/j.jlr.2023.100456