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Self-emulsifying micelles as a drug nanocarrier system for itraconazole oral bioavailability enhancement; in vitro and in vivo assessment

Itraconazole (ITZ) is a renowned antifungal medication, however its therapeutic efficacy is limited by low solubility and oral bioavailability. The current research work attempted to augment the oral bioavailability of ITZ by incorporating into self-emulsifying micelles (SEMCs). To fabricate the SEM...

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Detalles Bibliográficos
Autores principales: Islam, Nayyer, Ullah Khan, Naveed, Razzaq, Anam, Ullah Khan, Zaheer, Menaa, Farid, Alfaifi, Mohammad Y., Elbehairi, Serag Eldin I., Iqbal, Haroon, Ni, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641562/
https://www.ncbi.nlm.nih.gov/pubmed/37965489
http://dx.doi.org/10.1016/j.jsps.2023.101839