miRNA-381 regulates renal cancer stem cell properties and sunitinib resistance via targeting SOX4

Cancer stem cells (CSCs) are crucial in the pathogenesis of human cancers. Existing studies reported that microRNA (miRNA) modulates the stemness of CSCs. We discovered that renal cell CSCs have suppressed miR-381. Suppression of miR-381 promotes renal cell tumorigenesis and CSC-like properties. Fur...

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Detalles Bibliográficos
Autores principales: Lu, Xiao-jun, Gao, Wen-wen, Li, Jia-cheng, Qin, Sheng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641571/
https://www.ncbi.nlm.nih.gov/pubmed/37965067
http://dx.doi.org/10.1016/j.bbrep.2023.101566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641571/
https://www.ncbi.nlm.nih.gov/pubmed/37965067
http://dx.doi.org/10.1016/j.bbrep.2023.101566

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