Cargando…
miRNA-381 regulates renal cancer stem cell properties and sunitinib resistance via targeting SOX4
Cancer stem cells (CSCs) are crucial in the pathogenesis of human cancers. Existing studies reported that microRNA (miRNA) modulates the stemness of CSCs. We discovered that renal cell CSCs have suppressed miR-381. Suppression of miR-381 promotes renal cell tumorigenesis and CSC-like properties. Fur...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641571/ https://www.ncbi.nlm.nih.gov/pubmed/37965067 http://dx.doi.org/10.1016/j.bbrep.2023.101566 |