Pulmonary hypertension associated with diazoxide: the SUR1 paradox

The ATP-sensitive potassium channels and their regulatory subunits, sulfonylurea receptor 1 (SUR1/Kir6.2) and SUR2/Kir6.1, contribute to the pathophysiology of pulmonary hypertension (PH). Loss-of-function pathogenic variants in the ABCC8 gene, which encodes for SUR1, have been associated with herit...

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Detalles Bibliográficos
Autores principales: Montani, David, Antigny, Fabrice, Jutant, Etienne-Marie, Chaumais, Marie-Camille, Le Ribeuz, Hélène, Grynblat, Julien, Khouri, Charles, Humbert, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641583/
https://www.ncbi.nlm.nih.gov/pubmed/37965230
http://dx.doi.org/10.1183/23120541.00350-2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641583/
https://www.ncbi.nlm.nih.gov/pubmed/37965230
http://dx.doi.org/10.1183/23120541.00350-2023

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