How sequence alterations enhance the stability and delay expansion of DNA triplet repeat domains

DNA sequence alterations within DNA repeat domains inexplicably enhance the stability and delay the expansion of interrupted repeat domains. Here we propose mechanisms that rationalise such unanticipated outcomes. Specifically, we describe how interruption of a DNA repeat domain restricts the ensemb...

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Detalles Bibliográficos
Autores principales: Völker, Jens, Breslauer, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641665/
https://www.ncbi.nlm.nih.gov/pubmed/37965436
http://dx.doi.org/10.1017/qrd.2023.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641665/
https://www.ncbi.nlm.nih.gov/pubmed/37965436
http://dx.doi.org/10.1017/qrd.2023.6

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