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How sequence alterations enhance the stability and delay expansion of DNA triplet repeat domains
DNA sequence alterations within DNA repeat domains inexplicably enhance the stability and delay the expansion of interrupted repeat domains. Here we propose mechanisms that rationalise such unanticipated outcomes. Specifically, we describe how interruption of a DNA repeat domain restricts the ensemb...
Autores principales: | Völker, Jens, Breslauer, Kenneth J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641665/ https://www.ncbi.nlm.nih.gov/pubmed/37965436 http://dx.doi.org/10.1017/qrd.2023.6 |
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