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A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways

Mis-folding of the prion protein (PrP) is known to cause neurodegenerative disease; however, the native function of this protein remains poorly defined. PrP has been linked with many cellular functions, including cellular proliferation and senescence. It is also known to influence epidermal growth f...

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Detalles Bibliográficos
Autores principales: Groveman, Bradley R., Schwarz, Benjamin, Bohrnsen, Eric, Foliaki, Simote T., Carroll, James A., Wood, Aleksandar R., Bosio, Catharine M., Haigh, Cathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641666/
https://www.ncbi.nlm.nih.gov/pubmed/37802314
http://dx.doi.org/10.1016/j.jbc.2023.105319