Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton

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Just under the plasma membrane of most animal cells lies a dense meshwork of actin filaments called the cortical cytoskeleton. In insulin-secreting pancreatic β cells, a long-standing model posits that the cortical actin layer primarily acts to restrict access of insulin granules to the plasma membr...

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Detalles Bibliográficos
Autores principales: Polino, Alexander J., Ng, Xue Wen, Rooks, Rebecca, Piston, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641669/
https://www.ncbi.nlm.nih.gov/pubmed/37827287
http://dx.doi.org/10.1016/j.jbc.2023.105334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641669/
https://www.ncbi.nlm.nih.gov/pubmed/37827287
http://dx.doi.org/10.1016/j.jbc.2023.105334

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