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SGCE promotes breast cancer stemness by promoting the transcription of FGF-BP1 by Sp1

Breast cancer stem cells are mainly responsible for poor prognosis, especially in triple-negative breast cancer (TNBC). In a previous study, we demonstrated that ε-Sarcoglycan (SGCE), a type Ⅰ single-transmembrane protein, is a potential oncogene that promotes TNBC stemness by stabilizing EGFR. Here...

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Detalles Bibliográficos
Autores principales: Qiu, Ting, Hou, Lei, Zhao, Lina, Wang, Xinye, Zhou, Zhongmei, Yang, Chuanyu, Zhang, Huifeng, Jiang, Dewei, Jiao, Baowei, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641673/
https://www.ncbi.nlm.nih.gov/pubmed/37838174
http://dx.doi.org/10.1016/j.jbc.2023.105351