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Identification of the immune-associated characteristics and predictive biomarkers of keratoconus based on single-cell RNA-sequencing and bulk RNA-sequencing

BACKGROUND: Whether keratoconus (KC) is an inflammatory disease is currently debated. Hence, we aimed to investigate the immune-related features of KC based on single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (bulk RNA-seq) data. METHODS: scRNA-seq data were obtained from the Genome Se...

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Detalles Bibliográficos
Autores principales: Niu, Xiaoguang, Xu, Man, Zhu, Jian, Zhang, Shaowei, Yang, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641680/
https://www.ncbi.nlm.nih.gov/pubmed/37965330
http://dx.doi.org/10.3389/fimmu.2023.1220646