Extensive mutational ctDNA profiles reflect High-grade serous cancer tumors and reveal emerging mutations at recurrence

OBJECTIVE: Circulating tumor DNA (ctDNA) offers a minimally-invasive alternative to study genomic changes in recurrent malignancies. With a high recurrence rate, the overall survival in high-grade serous ovarian carcinoma (HGSC) has remained low. Our objectives were to determine whether ctDNA from p...

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Detalles Bibliográficos
Autores principales: Marchi, Giovanni, Rajavuori, Anna, Nguyen, Mai T.N., Huhtinen, Kaisa, Oksa, Sinikka, Hietanen, Sakari, Hautaniemi, Sampsa, Hynninen, Johanna, Oikkonen, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641709/
https://www.ncbi.nlm.nih.gov/pubmed/37924564
http://dx.doi.org/10.1016/j.tranon.2023.101814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641709/
https://www.ncbi.nlm.nih.gov/pubmed/37924564
http://dx.doi.org/10.1016/j.tranon.2023.101814

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