CAR-T cells and CAR-Tregs targeting conventional type-1 dendritic cell suppress experimental autoimmune encephalomyelitis

Conventional type 1 dendritic cells (DC1) contribute to the development of pathogenic T helper type 1 (Th1) cells in part via the production of the proinflammatory cytokine interleukin-12. Thus, depletion of DC1 has the potential to dampen autoimmune responses. Here, we developed X-C motif chemokine...

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Detalles Bibliográficos
Autores principales: Moorman, Cody D., Yu, Sherman, Briseno, Carlos G., Phee, Hyewon, Sahoo, Anupama, Ramrakhiani, Ambika, Chaudhry, Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641730/
https://www.ncbi.nlm.nih.gov/pubmed/37965348
http://dx.doi.org/10.3389/fimmu.2023.1235222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641730/
https://www.ncbi.nlm.nih.gov/pubmed/37965348
http://dx.doi.org/10.3389/fimmu.2023.1235222

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