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Expansion of extrafollicular B and T cell subsets in childhood-onset systemic lupus erythematosus

INTRODUCTION: Most childhood-onset SLE patients (cSLE) develop lupus nephritis (cLN), but only a small proportion achieve complete response to current therapies. The prognosis of children with LN and end-stage renal disease is particularly dire. Mortality rates within the first five years of renal r...

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Detalles Bibliográficos
Autores principales: Baxter, Ryan M., Wang, Christine S., Garcia-Perez, Josselyn E., Kong, Daniel S., Coleman, Brianne M., Larchenko, Valentyna, Schuyler, Ronald P., Jackson, Conner, Ghosh, Tusharkanti, Rudra, Pratyaydipta, Paul, Debdas, Claassen, Manfred, Rochford, Rosemary, Cambier, John C., Ghosh, Debashis, Cooper, Jennifer C., Smith, Mia J., Hsieh, Elena W. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641733/
https://www.ncbi.nlm.nih.gov/pubmed/37965329
http://dx.doi.org/10.3389/fimmu.2023.1208282