Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells

The activating receptor natural killer group 2, member D (NKG2D) represents an attractive target for immunotherapy as it exerts a crucial role in cancer immunosurveillance by regulating the activity of cytotoxic lymphocytes. In this study, a panel of novel NKG2D-specific single-chain fragments varia...

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Detalles Bibliográficos
Autores principales: Lutz, Sebastian, Klausz, Katja, Albici, Anca-Maria, Ebinger, Lea, Sellmer, Lea, Teipel, Hannah, Frenzel, André, Langner, Anna, Winterberg, Dorothee, Krohn, Steffen, Hust, Michael, Schirrmann, Thomas, Dübel, Stefan, Scherließ, Regina, Humpe, Andreas, Gramatzki, Martin, Kellner, Christian, Peipp, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641740/
https://www.ncbi.nlm.nih.gov/pubmed/37965326
http://dx.doi.org/10.3389/fimmu.2023.1227572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641740/
https://www.ncbi.nlm.nih.gov/pubmed/37965326
http://dx.doi.org/10.3389/fimmu.2023.1227572

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