Structural basis of aggregate binding by the AAA+ disaggregase ClpG

Severe heat stress causes massive loss of essential proteins by aggregation, necessitating a cellular activity that rescues aggregated proteins. This activity is executed by ATP-dependent, ring-forming, hexameric AAA+ disaggregases. Little is known about the recognition principles of stress-induced...

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Detalles Bibliográficos
Autores principales: Katikaridis, Panagiotis, Simon, Bernd, Jenne, Timo, Moon, Seongjoon, Lee, Changhan, Hennig, Janosch, Mogk, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641755/
https://www.ncbi.nlm.nih.gov/pubmed/37827289
http://dx.doi.org/10.1016/j.jbc.2023.105336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641755/
https://www.ncbi.nlm.nih.gov/pubmed/37827289
http://dx.doi.org/10.1016/j.jbc.2023.105336

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