RelB-activated GPX4 inhibits ferroptosis and confers tamoxifen resistance in breast cancer

Tamoxifen (TAM) resistance remains a major obstacle in the treatment of advanced breast cancer (BCa). In addition to the competitive inhibition of the estrogen receptor (ER) signaling pathway, damping of mitochondrial function by increasing reactive oxygen species (ROS) is critical for enhancing TAM...

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Detalles Bibliográficos
Autores principales: Xu, Zhi, Wang, Xiumei, Sun, Wenbo, Xu, Fan, Kou, Hengyuan, Hu, Weizi, Zhang, Yanyan, Jiang, Qin, Tang, Jinhai, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641764/
https://www.ncbi.nlm.nih.gov/pubmed/37944384
http://dx.doi.org/10.1016/j.redox.2023.102952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641764/
https://www.ncbi.nlm.nih.gov/pubmed/37944384
http://dx.doi.org/10.1016/j.redox.2023.102952

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