IFN-γ lowers tumor growth by increasing glycolysis and lactate production in a nitric oxide-dependent manner: implications for cancer immunotherapy

INTRODUCTION: Interferon-gamma (IFN-γ), the sole member of the type-II interferon family, is well known to protect the host from infectious diseases as well as mount anti-tumor responses. The amounts of IFN-γ in the tumor microenvironment determine the host responses against tumors; however, several...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Avik, Jagdish, Sirisha, Karhale, Aagosh Kishor, Ramteke, Nikita S., Zaib, Arsha, Nandi, Dipankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641808/
https://www.ncbi.nlm.nih.gov/pubmed/37965321
http://dx.doi.org/10.3389/fimmu.2023.1282653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641808/
https://www.ncbi.nlm.nih.gov/pubmed/37965321
http://dx.doi.org/10.3389/fimmu.2023.1282653

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