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IFN-γ lowers tumor growth by increasing glycolysis and lactate production in a nitric oxide-dependent manner: implications for cancer immunotherapy
INTRODUCTION: Interferon-gamma (IFN-γ), the sole member of the type-II interferon family, is well known to protect the host from infectious diseases as well as mount anti-tumor responses. The amounts of IFN-γ in the tumor microenvironment determine the host responses against tumors; however, several...
Autores principales: | Chattopadhyay, Avik, Jagdish, Sirisha, Karhale, Aagosh Kishor, Ramteke, Nikita S., Zaib, Arsha, Nandi, Dipankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641808/ https://www.ncbi.nlm.nih.gov/pubmed/37965321 http://dx.doi.org/10.3389/fimmu.2023.1282653 |
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