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Addressing Motor Dysfunction by a Selective α6-Containing Nicotinic Receptor Antagonist

In the striatum, presynaptic α6-containig nicotinic receptors are crucially involved in the modulation of dopamine release. CVN417, a novel selective antagonist at this receptor subtype, attenuates motor dysfunction in a Parkinson’s disease-relevant animal model, suggesting, for this pathology, a th...

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Detalles Bibliográficos
Autores principales:	Bolchi, Cristiano, Pallavicini, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641822/ https://www.ncbi.nlm.nih.gov/pubmed/37852222 http://dx.doi.org/10.1021/acs.jmedchem.3c01817

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