Identification of HuR–RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization

[Image: see text] The RNA binding protein HuR regulates the post-transcriptional process of different oncogenes and tumor suppressor genes, and its dysregulation is linked with cancer. Thus, modulating the complex HuR–RNA represents a promising anticancer strategy. To search for novel HuR ligands ab...

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Detalles Bibliográficos
Autores principales: Volpe, Serena Della, Listro, Roberta, Ambrosio, Francesca Alessandra, Garbagnoli, Martina, Linciano, Pasquale, Rossi, Daniela, Costa, Giosuè, Alcaro, Stefano, Vasile, Francesca, Hirsch, Anna K. H., Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641899/
https://www.ncbi.nlm.nih.gov/pubmed/37970588
http://dx.doi.org/10.1021/acsmedchemlett.3c00303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641899/
https://www.ncbi.nlm.nih.gov/pubmed/37970588
http://dx.doi.org/10.1021/acsmedchemlett.3c00303

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