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Identification of HuR–RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization

[Image: see text] The RNA binding protein HuR regulates the post-transcriptional process of different oncogenes and tumor suppressor genes, and its dysregulation is linked with cancer. Thus, modulating the complex HuR–RNA represents a promising anticancer strategy. To search for novel HuR ligands ab...

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Detalles Bibliográficos
Autores principales:	Volpe, Serena Della, Listro, Roberta, Ambrosio, Francesca Alessandra, Garbagnoli, Martina, Linciano, Pasquale, Rossi, Daniela, Costa, Giosuè, Alcaro, Stefano, Vasile, Francesca, Hirsch, Anna K. H., Collina, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641899/ https://www.ncbi.nlm.nih.gov/pubmed/37970588 http://dx.doi.org/10.1021/acsmedchemlett.3c00303

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